for veterinary use only with a prescription
COMPOSITION:
Each ml Tetraplex contains
Oxytetracycline (as hydrochloride) 200 mg
Description:
Oxytetracycline is a broad-spectrum antibiotic with a bacteriostatic action against both gram-positive and gram-negative bacteria, with the exception of Pseudomonas, Klebsiella, and Proteus spp. The antibacterial spectrum of oxytetracycline includes furthermore Leptospires, Spirochetes, Actinomyces, Rickettsia, Bedsonia, some Mycoplasms, and some Protozoa.
The bacteriostatic effect of oxytetracycline is based on the inhibition of glutamic acid metabolism in the cells, thus inhibiting the synthesis of bacterial proteins.
The development of bacterial resistance to tetracyclines increasing among many bacterial species; resistance is occurring especially in Pseudomonas, Klebsiella, Aerobacter, Enterococci, and Proteus. Cross-resistance between tetracyclines is complete.
After intramuscular administration of this formulation, therapeutic blood concentrations of oxytetracycline are retained for at least 60 to 72 hours (>0.1 mcg/ml) due to the special formulation and dosage Schedule.
Excretion takes place mainly, via kidneys in unchanged form and partly via the bile.
Target animals:
Cattle, camel, sheep, and goats.
Indications:
Tetraplex for treatment of Infections caused by bacteria susceptible to oxytetracycline particularly pneumonia, pasteurellosis, anaplasmosis and chlamydiosis.
Treatment of respiratory, gastrointestinal, urogenital system infections, soft tissue infections.
Contraindications:
Hypersensitivity to tetracyclines;
Administration of Tetraplex to animals existing hepatic and/or renal insufficiency;
Administration to animals during the last two months of pregnacy.
Administration to other animals as listed under the indications.
(i.e. contraindicated in horses, cats and dogs)
Side-effects:
Local irritation has been noticed at the injection site, but this local reaction disappears within about 5 days after injection.
Route of administration and dosage:
Tetraplex is for intramuscular or SC administration.
The general recommended single dose is 20 mg oxytetracycline per kg body weight, or 1 ml per 10 kg body weight.
Withdrawal times:
Meat: 28 days.
Milk: Not used in animals producing milk for human consumption
Shelf life and storage:
Tetraplex should be stored at room temperature (15-25 °C) and protected from moisture, light, and heat.
